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TorresPJSiakowskaMBanaszewskaBPawelczykLDulebaAJKelleySTet al

In humans, insulin-like growth factor type 1 (IGF-1) and several of its binding proteins are positively associated with acquisition of PBM and the maintenance of bone mineral density (BMD) (911) and low IGF-1 levels have been found to be a risk factor for osteoporosis and fracture risk (3,1219)

The manufacturer recommends to give 1 mL by mouth per day for cats and small dogs, 2 mL by mouth per day for medium sized dogs (25-50 lbs), and 3 mL by mouth per day for large sized dogs (50-100 lbs)

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2010 Sep;95(9):4291-304

Track your weekly weight at the same time of day, wearing similar clothing, using the same scale