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Preclinical rodent evidence supports retained activity after oral administration, particularly for GI-specific endpoints and (with higher doses) for systemic endpoints
nor were there significant differences in calcium stones or pain relief
(PubMed) Kushi LH, Folsom AR, Prineas RJ, Mink PJ, Wu Y, Bostick RM
LIF/STAT3/SOCS3 signaling pathway in murine bone marrow stromal cells suppresses osteoblast differentiation
Preliminary data has been collected and showed an overall increase in the number of visible nodes on higher magnification levels, as well as an increased prevalence of V, X, and especially Y nodes with these higher levels of magnification
