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However, you should contact your GP for persistent symptoms, NHS 111 for urgent concerns, or attend A&E if you experience severe, persistent vomiting, signs of dehydration (dark urine, dizziness, reduced urination), severe abdominal pain (especially if radiating to the back), or symptoms of gallbladder problems (severe upper right abdominal pain, fever, yellowing of skin/eyes)

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TRANSCEND-T2D-1 (NCT06354660) reported topline results on March 19, 2026, with full publication in The Lancet in June 2026