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The SELECT trial was the first large, randomized study to show that a drug used for obesity could reduce cardiovascular disease, says Isaacs

doi: 10.1210/jc.2018-02685

Normal eGFR varies by age and decreases as you get older, but a higher number is better, typically equal to or above 60

This medicine is contraindicated in patients with known allergies to any of the active ingredients: Folic Acid, L-Carnitine / Levocarnitine, or Methylcobalamin

This guide explains those side effects in clear, simple language

While safety data from this trial is encouraging, the sample size is too small for any meaningful conclusions to be drawn