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It has been evidenced that antioxidative, apoptosis and Ca + + flux can be muffled via transient receptor potential vanilloid 1(TRPV1) channel in the neutrophils of PCOS patients, where the potential role might be the anti-inflammatory turnouts and the improvement of the insulin resistance [190]
Elevated zonulin levels have been found in patients with rheumatoid arthritis, multiple sclerosis or ankylosing spondylitis [1, 73,74,75]
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