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For individuals with digestive sensitivities, those taking acid-reflux medications, or anyone on a plant-based (vegan/vegetarian) diet, absorbing enough B12 through food or pills is virtually impossible
Liver Int 40(7):16551669
This delayed gastric emptyinga key mechanism for reducing appetitecan also delay absorption of oral medications, including antibiotics
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Supports Gut Microbiome Diversity Helps promote a more balanced intestinal ecosystem
Its activity intersects two major metabolic pathways simultaneously: the NAD+ biosynthesis pathway (by consuming nicotinamide, an NAD+ precursor, NNMT competes with the NAD+ salvage pathway) and the methyl-donor pathway (by consuming SAM, NNMT reduces the availability of methyl groups for epigenetic and metabolic methylation reactions)
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