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Tirzepatide at its starting dose of 2.5mg may take longer to produce noticeable appetite effects because this dose is primarily intended for tolerability rather than efficacy
David Sinclair, Life Biosciences co-founder (Jemal Countess/Getty Images for TIME) David Sinclair startup raises $80M for clinical test of anti-aging gene therapy A startup developing a one-time treatment that is intended to rewind the clock on dying cells announced a major influx of funding
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3 Adverse effects 3.1 Gastrointestinal effects Despite its widespread availability and affordability, metformin is associated with gastrointestinal side effects, including nausea, vomiting, diarrhea, and bloating, affecting around 20% of patients (Sanchez-Rangel and Inzucchi, 2017
Individuals with type 2 diabetes face a 1.7-fold higher risk of developing dementia 31
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