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For example, damage-associated molecular patterns (DAMPs) or KRAS G12D proteins released from ferroptotic cells can be packaged into exosomes and internalized by macrophages, transforming them into the M2-like phenotype and leading to an immunosuppressive environment [118]
However, these drugs have side effects, including gastrointestinal upset and nausea
Editors note: The study is called Efficacy of GLP-1 Receptor Agonists in Treating Upper and Lower Extremity Lymphedema
Diabetes Obes Metab 2023;25:3724-35.PubMed 51
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