Indeed, the data above show that all forms of vitamin B12 administered to patients with deficiency are catalyzed at this stage by glutathione, during which all axial Co-C or Co-O chemical bonds are broken, and the central cobalt atom of all forms receives an electron or a large part of the electron density reaching one electron during the reaction from the monoanion of glutathione
85 KhalafS.AhmadA
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J Thyroid Res
in the mid-1930s [26], (b) produced mainly by fibroblasts [27], (c) to date consists of 28 types, numbered from IXXVIII, constituting about 8090% (type I) and 1015% (type III) in human skin [27], (d) provides tensile strength and elasticity to withstand mechanical forces in everyday activities [26,27,28,29], and (e) mainly composed of the amino acids glycine (Gly), proline (Pro), and hydroxyproline (Hyp), along with its typical triple-helix structure [26, 27, 29]
