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Preventing Complications of Insulin Therapy Insulin administration can sometimes lead to local and systemic allergic reactions, with local reactions causing redness, swelling, tenderness, and wheals at the injection site

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Kaufman-Janette J, Joseph JH, Kaminer MS, Clark J, Fabi SG, Gold MH, Goldman MP, Katz BE, Peddy K, Schlessinger J, Young VL, Davis M, Hurley D, Liu G, McLane MP, Vijayan S, Bass LS