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bioRxiv 8 May 24 Functional and multi-omic aging rejuvenation with GLP-1R agonism Identifying readily implementable methods that can effectively counteract aging is urgently needed for tackling age-related degenerative disorders
This provided an ideal setting to begin his hunt for the putative GIP
P.g administration also induces significant fungal dysbiosis (mycobiome), enriching pathogenic species such as Pyricularia pennisetigena , Alternaria alternata , and Candida glabrata , which correlate with alterations in host metabolic pathways, especially tryptophan metabolism ( P.g and its metabolites directly and indirectly compromise gut integrity by downregulating the expression of tight junction proteins (ZO-1, Occludin, Claudins) and mucins (MUC2), leading to increased intestinal permeability (Tsuzuno et al., 2021
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