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Although normal electron transport in mitochondria involves four-electron reduction of O 2 to water, partial reduction reactions occur under physiological conditions, causing release of superoxide anion and hydrogen peroxide (H 2 O 2 )

A presentation last year at the Special Operations Medical Association reported that supplement use in the military runs as high as 74 percent, and is likely higher still in the special operations community

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doi: 10.1016/j.ijporl.2008.05.017

this is the conservative upper end for most research protocols