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FASN can bind to hypoxia-inducible factor 1-alpha (HIF-1) to prompt its translocation, suppress its ubiquitination and proteasomal degradation, and then increase the transcription of SLC7A11 , thus resulting in the cellular confrontation to ferroptosis [97]
24 h) activates the FAK-paxillin pathway in cultured SD rat Achilles tendon fibroblasts [1]
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Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial
SLC7A11/xCT prevents cardiac hypertrophy by inhibiting ferroptosis
Xu HY, Liu YQ, Wang JN, Jin XQ (2023) Short-term effects of ambient air pollution on emergency department visits for urolithiasis: A time-series study in Wuhan, China
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