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HOW MOTS-C PEPTIDE REGULATES GLUCOSE Clinical studies have shown that MOTS-c promotes the production of endogen AMP analogue AICAR, which in turn, helps in the synthesis of AMP-activated protein kinase [1] (also referred to as AMPK)

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J Neurotrauma 31:649657 Catroppa C, Godfrey C, Rosenfeld JV, Hearps SS, Anderson VA (2012) Functional recovery ten years after pediatric traumatic brain injury: outcomes and predictors

They are essential for maintaining T-cell homeostasis and exert effects such as anti-inflammatory and immunomodulatory actions, downregulation of the Wnt/-catenin signaling pathway associated with CRC, restriction of tumor cell growth and migration, inhibition of tumor development, induction of apoptosis, and promotion of CRC cell differentiation [178,179,180]

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