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The LD control group was particularly distinct from the other groups in the unweighted UniFrac and BrayCurtis dissimilarity analyses plots, suggesting that animals exposed to the same diet at an early age in life diet develop similar microbiome profiles that persist even after an acute change in diet

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[11] By ramping up the dosage slowly, patients can often avoid side effects like headache or nausea while still obtaining the energizing or cognitive benefits of NAD+