El GLP-1 ha servido de desarrollo de toda una familia farmacolgica (los arGLP-1), mientras que el GIP no ha conducido a un desarrollo similar, probablemente porque sus efectos insulinotrpicos estn alterados en las personas con DM2, a pesar de que los efectos insulinotrpicos del GIP pueden ser restaurados tras 4 semanas de normalizacin de la hiperglucemia con insulina en pacientes con DM2
Comparing them is not about declaring a winner, but about understanding how research evolves from a generalist agonist to a targeted one
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A heatmap was plotted using the heatmap3 package
Auton Neurosci 110(1):3643 Koda S et al (2005) The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats