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Errors during reconstitution or storage directly impact effectiveness and safety

It is also vital for red blood cell health, energy production and DNA replication and repair and has a role to play in breaking down the amino acid homocysteine, high levels of which have been linked to an increased risk of heart disease, stroke and dementia

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There is no evidence that doses above 500mcg produce proportionally better results, and clinical trials using 1mg daily did not dramatically outperform lower doses