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The decreased proliferative ability of the ADSCs can affect the response to oxidative damage, the production of cytokines and the activity of fibroblasts
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Host factors further rewire this axis: SARS-CoV-2 proteins perturb IRS adaptors and upregulate suppressor of cytokine signaling-3, blunting Akt and contributing to de novo insulin resistance (human mechanistic/observational), while estrogen receptor- scaffolds IRS-1 to bolster AktmTORC2 (mechanistic
C chia s: i s thng hiu l ngi i din nhn hng khng ch v mt hnh nh m cn bi s tng ng gia tnh cch bn thn v thng hiu
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