Eli Lilly reported dysesthesia was "generally mild" and "rarely led to discontinuation." TRIUMPH-1 the larger general obesity trial with 2,339 patients at 80 weeks confirmed dysesthesia at 12.5% on the 12mg dose, substantially lower than TRIUMPH-4's 20.9%
So, in sort of the bariatric endoscopy and bariatric surgery realm, we advocate for more of a combined approach. That could include bariatric surgery or endoscopy followed by a short course of GLP-1 medications
Not affiliated: PlexusDx has no relationship with Found or with the manufacturer of Wegovy and runs its own compounded protocols through licensed 503A pharmacies
Brands should not imply that these ingredients help people taking GLP-1 medications maintain muscle unless the claim is supported by evidence that is relevant to GLP-1 users, the finished formulation, and the intended serving size
Short-acting preparations include beinaglutide (BN) and exenatide (EX), which generally need to be injected 2-3 times a day
When I talk about GLP-1 agonists, Im talking about both of them