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Diets high in refined carbohydrates cause sugar spikes that trigger glycation , a process where excess glucose binds to collagen and elastin, making them rigid and the skin less elastic

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In the landmark STEP-1 clinical trial, participants receiving semaglutide 2.4 mg once weekly lost an average of 14.9% of their body weight over 68 weeks, compared to 2.4% with placebo

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