Many patients prescribed Saxenda (liraglutide) for weight management also take fluoxetine for depression or other mental health conditions
While this percentage might seem small, it is significant enough to warrant attention
In addition to the glucose-lowering effects associated with GLP-1R agonism, GCGR agonism, via receptors in the liver, may lead to increased energy expenditure [7, 8]
Being lean without muscle mass is not a healthy state either. But it could be that the mices running is more like a compulsion
For someone starting at 230 pounds, that translates to roughly 52 pounds of weight loss
The dual mechanism of tirzepatide produces greater average weight loss in clinical trials, approximately 22% body weight versus 15% for semaglutide