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Informed consent should include what is known, what is unknown, whether the formulation is approved, and what alternatives have stronger evidence
5 days/week (~12 mg/day): ~13 vials 3/week (2 mg): ~12 vials 16 weeks: ~3 vials Insulin Syringes (U-100, 1 mL) Per injection: 1 syringe 8 weeks (5 days/week): ~40 syringes 16 weeks (5 days/week): ~80 syringes Bacteriostatic Water (10 mL bottles) Use ~3.0 mL per 50 mg vial for reconstitution
Common side effects are mild: injection site redness, temporary fatigue, and occasional nausea
Important safety notes apply to any multi-peptide protocol
McGraw-Hill Education
One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12
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