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At the epidemiological observation level, prospective cohort studies have confirmed the predictive value of baseline metabolite concentrations for subsequent disease progression, with current evidence strength graded as moderate (159)
10.3390/ijms23126846 Int
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For example, chondrocytes isolated from OA cartilage displayed significant senescence levels, and ABT263 treatment reduced the expression of inflammatory cytokines and promoted cartilage matrix aggregation in OA chondrocytes ( Next, we tested the potential of FOXO4-DRI in removing senescent chondrocytes, which has not been reported before
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