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Day 1 Breakfast: Protein oatmeal cup oats, 1 scoop vanilla protein powder, cup berries, 1 tbsp chia seeds (~30g protein | ~7g fiber) Lunch: Grilled chicken salad 5oz grilled chicken, avocado, cup cucumber, cup cherry tomatoes, 1 tbsp olive oil vinaigrette (~35g protein | ~6g fiber) Dinner: 5oz salmon, 1 cup roasted broccoli, cup roasted sweet potato (~30g protein | ~7g fiber) Snack: cup Greek yogurt with cup berries (~15g protein | ~2g fiber) Day 2 Breakfast: Greek yogurt bowl cup Greek yogurt, cup berries, 1 tbsp hemp seeds, cinnamon to taste (~25g protein | ~4g fiber) Lunch: Chicken taco bowl 5oz grilled chicken, 1 cup lettuce, cup black beans, avocado, cup salsa (~38g protein | ~10g fiber) Dinner: Sheet pan chicken 6oz chicken breast, 1 cup broccoli, 1 cup zucchini, onion, 1 tbsp olive oil (~35g protein | ~6g fiber) Snack: cup cottage cheese with cup fruit (~15g protein | ~2g fiber) Day 3 Breakfast: Protein smoothie 1 scoop protein powder, 1 cup spinach, cup berries, 1 cup almond milk, ice (~28g protein | ~5g fiber) Lunch: Grilled chicken bowl 5oz grilled chicken, cup cooked quinoa, 1 cup roasted vegetables, 1 tsp olive oil drizzle (~38g protein | ~8g fiber) Dinner: Turkey taco salad 5oz ground turkey, 1 cups lettuce, cup tomatoes, avocado, cup salsa (~35g protein | ~7g fiber) Snack: 2 hard-boiled eggs and 1 medium apple (~13g protein | ~4g fiber) Day 4 Breakfast: Oats with almond butter cup oats, 1 scoop protein powder, 1 tbsp almond butter, 1 tbsp chia seeds, cup mixed berries (~33g protein | ~6g fiber) Lunch: Grilled chicken with quinoa and roasted vegetables 4oz grilled chicken breast, cup cooked quinoa, 1 cup steamed or roasted vegetables, 1 tsp olive oil drizzle (~38g protein | ~8g fiber) Dinner: Baked salmon with sweet potato and green beans 45oz baked salmon, cup roasted sweet potato cubed, 1 cup steamed broccoli or green beans (~45g protein | ~6g fiber) Snack: Greek yogurt with berries cup plain Greek yogurt, cup mixed berries, 1 tsp chia seeds (~20g protein | ~2g fiber) Disclaimer: This sample meal plan is for educational purposes only

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Research-grade semaglutide reconstituted in bacteriostatic water typically follows the conservative 28-to-30-day guideline

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doi: 10.1210/en.2007-1292 Summary Keywords GLP-1, DPP-4, fracture, diabetes, bone, osteoporosis, antidiabetic, glucose-lowering drugs Citation Al-Mashhadi ZK, Viggers R, Fuglsang-Nielsen R, Vestergaard P, Gregersen S and Starup-Linde J (2022) The risk of major osteoporotic fractures with GLP-1 receptor agonists when compared to DPP-4 inhibitors: A Danish nationwide cohort study