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Important precautions include: GLP-1 receptor agonists should not be used in patients with type 1 diabetes or diabetic ketoacidosis Caution is advised in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 These medications are not recommended in severe gastrointestinal disease They should not be used during pregnancy or breastfeeding, and semaglutide should be discontinued at least 2 months before a planned pregnancy [1] [7] Your GP or specialist will assess your individual circumstances to determine suitability
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doi: 10.1007/s12020-021-02642-z 54 ToulisKAAnastasilakisADTzellosTGGoulisDGKouvelasD
3,4 This receptor and its agonists hold significant therapeutic potential, reshaping the treatment approaches for multiple diseases, including diabetes, cardiovascular disorders, and neurodegenerative diseases
