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Rybelsus is prescription-only and has been available in Germany since July 2025
Animal preparation Adult male Sprague-Dawley rats weighing 220250 g or transgenic mice (see below) were anaesthetised with pentobarbital sodium (induction 60 mg/kg i.p
Accurate documentation of dose, route, date, and reason for holding allows others to intervene without constant calling or guesswork
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IPGTT was performed every 4 to 5 weeks (see ESM Methods)
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