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Dihydroxylated flavonoids exhibit greater electron-donating capacity and stabilize hydroxyl radicals more efficiently than monohydroxylated derivatives, whereas their metal-chelating properties suppress ROS propagation through the Fenton reaction (Shomali et al., 2022)

Crucially, its efficacy in large-scale cardiovascular outcome trials remains unproven, leaving it as a theoretically interesting but clinically unvalidated option in an era dominated by well-established, evidence-backed reperfusion strategies

United Kingdom (London): IntechOpen (2022)

The timeline depends on baseline pigmentation, skin type, lifestyle, and sun exposure

Studies show persistent elevation of vascular injury markers such as vWF and cytokines, suggesting ongoing thromboinflammation and hypercoagulable states in Long COVID [362, 363]