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patients receiving thyroid-hormone replacement or those with thyroid dysfunction should be monitored for changes in symptom control

Determinants of activity in glutaredoxins: an in vitro evolved Grx1-like variant of Escherichia coli Grx3

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This copper-binding tripeptide activates TGF-beta/SMAD pathway signaling, stimulates collagen I and III synthesis, upregulates TIMP-1 and TIMP-2 to protect collagen from degradation, and modulates gene expression across approximately 4,000 human genes