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Acetyl-L-carnitine exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity

Therefore, the CS regulation, at both enzymatic and epigenetic levels, plays a pivotal role in tumors, suggesting new druggable pathways for prevention and treatment of human cancer

doi:10.1016/j.jacl.2023.10.011

Hydration stands out as particularly important

Several other proteins containing CSDs domain swap suggesting a relationship between domain swapping and CSD reduction (Wouters et al., 2010)