According to the American Diabetes Association guidelines, GLP-1 receptor agonists like semaglutide with proven cardiovascular benefit are recommended for patients with type 2 diabetes who have established atherosclerotic cardiovascular disease and for appropriate candidates requiring weight management
Nitric Oxide Modulation: It helps regulate blood flow and vascular health by interacting with the Nitric Oxide (NO) system
JCEM case reports 1: Hansen KB, Svendstrup M, Lund A et al (2021) Once-weekly subcutaneous semaglutide treatment for persons with type 2 diabetes: realworld data from a diabetes outpatient clinic
Any concurrent use should only occur under specialist supervision such as an endocrinologist with regular monitoring of hormone levels, haematocrit, and cardiovascular markers
How These Medications Work in the Body Who May Be Suitable for Hormone Weight Loss Treatment Risks, Side Effects and MHRA Safety Guidance NHS and NICE Guidelines on Weight Management Medicines Alternatives and Wider Support for Weight Loss in the UK Scientific References Frequently Asked Questions What Are Hormone-Based Weight Loss Medications
While findings from this new study are encouraging, more robust and long-term research is needed before physicians can confidently prescribe GLP-1 medications to non-diabetic patients with obesity specifically for cancer risk reduction, he said.