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GLP-1 is secreted in response to nutrient ingestion, especially in response to meals high in fat and carbohydrates [14]
Research has characterised MT-IIs transient blood pressure and heart rate changes , documenting central autonomic melanocortin receptor-mediated cardiovascular effects following MT-II administration through hypothalamic MC4R activation of sympathoadrenal outflow
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If persistent irritation occurs, discontinuation is recommended
I mean, Ive opted to continue taking it
The significant weight loss achieved with GLP-1 therapy varies by agent and dosewith semaglutide 2.4mg (Wegovy) achieving approximately 15% body weight reduction at 68 weeks, while liraglutide 3mg (Saxenda) typically produces 5-8% weight loss
