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This concerns preclinical and experimental research

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The biggest benefit of B12 Shots over B12 supplements is that the injections are directly routed to the cells, instead of passing through the digestive tract

Similarly to asthma, mast cells, Th2 cells, basophils, and epithelial cells synthesize and release cytokines and chemokines (IL-3, IL-4, IL-5, IL-10, IL-13, GM-CSF, and RANTES), which are responsible for sustaining allergic inflammation and the associated oxidative/nitrosative stress (115)