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However, a critical analysis reveals a clear distinction between theoretical promise and established clinical evidence

For in vitro work, pharmaceutical grade purity at 98%+ is the minimum standard, and 99%+ is strongly preferred

Interestingly, GLP-1 is also produced directly in the CNS by preproglucagon neurons, predominantly in the brainstem (DAlessio, 2016

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GLP-1 medications commonly cause gastrointestinal side effects such as nausea, diarrhoea, constipation, and bloating, which may overlap with or potentially worsen existing IBS symptoms

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