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They demonstrated that pretreatment of cultured SOD1 G93A astrocytes with MitoQ was able to reduce the formation of superoxide and peroxynitrite radicals, protect motor neurons against oxidative damage and improve the ability of mitochondria to generate ATP (Cassina et al., G93A mouse model, treatment with MitoQ at the onset of disease also delayed the decline of mitochondrial function in the spinal cord, protected against motor neuron loss and astrogliosis in the spinal cord
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As the body adjusts to the dosage, they fade
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elegans initially enters a bacterial lawn using a simple rule-of-thumb based on bacterial cell density 64 but after several hours of exposure animals avoid lethal bacterial foods such as certain RNAi-expressing bacteria 14 , food spiked with exogenous toxins 14,32 , or pathogens 15,16,18,82
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