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The persistent inflammatory environment not only exacerbates oxidative stress but also promotes the recruitment and activation of additional immune cells, further perpetuating the autoimmune response [58]

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For example, alpha-fetoprotein (AFP), miR-122, and circulating TERT promoter mutations are biomarkers used for diagnostic screening of HBV-related HCC (Trung et al., 2020)

Researchers should use appropriate laboratory tools and equipment to ensure accurate and sterile results