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Int J Mol Sci (2019) 20(7):1584

Since their first report in 1990, SELEX technology has been continuously improved, 174,175 diversifying the selection and development of high-affinity aptamers

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[34] showed that treatment with the GLP-1 RAs exenatide and liraglutide reduced both systolic and diastolic BP by 1 to 5 mm Hg in patients with T2D, compared with some other anti-diabetic drugs, including insulin, glimepiride, and placebo