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In the obesity trial, maximal WL was achieved with retatrutide 12 mg after 48 weeks: -24.2% vs
Exenatide had 53% homology with GLP-1, had strong binding ability with GLP-1 receptor and was not easily degraded by DPP-4
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was supported by fellowships from Pfizer Australia, NHMRC, veski and the Victorian Cancer Agency
GLP-1 therapy should complement, not replace, appropriate lipid-lowering treatment according to NICE guidance
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