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Discussion Activation of antioxidant responses by Nrf2 The transcription factor, Nrf2, has emerged as a promising target for selective pharmacological stimulation of protective cellular pathways (Robledinos-Antn et al

There are many potential processes underlying MTX toxicity (Reference Chan and Cronstein33) , but no effective treatments to ameliorate the condition exist

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For example, the livers of polar bears and other large animals that live in cold climates contain large amounts of vitamin A, which have occasionally proven fatal to humans who have eaten them

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A small number will need extra bowel preparation or changes to medications