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Supramolecules-guided synthesis of brightly near-infrared Au 22 nanoclusters with aggregation-induced emission for bioimaging
100.66 Dhs
doi:10.1530/eje.0.1390552 Andersen NB, Malmlf K, Johansen PB, Andreassen TT, rtoft G, Oxlund H
the original rodent study used 5 mg/kg, which when scaled allometrically to human equivalents suggests doses in the 5-10 mg range for a 70 kg adult, though allometric scaling from mice to humans is an imprecise science
Both peptides appear well tolerated in the limited settings studied, but long-term systemic human safety is uncharacterized for each, and research-grade material carries unverified identity and purity
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