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aureus, E
He reports that most vegans show adequate B12 levels to make clinical deficiency unlikely, but they may show restricted activity of B12-related enzymes, leading to elevated homocysteine levels, which has been linked to increased risk of heart disease and stroke
Am J Physiol 1993;265(4 Pt 1):L374L381
The absence of interaction evidence across three independent pathways (CYP2C9, OATP1B1/1B3, BCRP) makes a pharmacokinetic interaction between these two compounds improbable
Together, these mechanisms are associated with appetite regulation and weight-management outcomes documented in clinical studies
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