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The 1.0mg dose is where weight loss accelerates

In some trials, early, weight-independent changes point to intrinsic anti-inflammatory actionan appealing feature for vascular brain protection

If symptoms significantly impact daily functioning beyond the first week at a new dose, consider extending that dose level for an additional four weeks before increasing

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Avoid excessive caffeine and alcohol, both of which have mild diuretic effects and can worsen nausea

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