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No serious adverse events, hospitalization, organ damage, or deaths have been documented in over 100 preclinical studies, even at doses 1,000 times higher than typical therapeutic use
Additionally, Epitalon exhibits antioxidant activity by reducing lipid peroxidation and regulating reactive oxygen species (ROS)
10.1016/j.ejphar.2011.05.038 50 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)
Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]
These are the glue that keeps the gut lining and vascular barriers intact, which is why it is often cited in discussions regarding leaky gut and systemic inflammation
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