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Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study

It enrolled adults with a body mass index of 30 or greater, or 27 or greater with at least one weight-related comorbidity, and randomized them across multiple retatrutide dose arms (1 mg, 4 mg, 8 mg, and 12 mg weekly) versus placebo

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Stimulants cause tolerance development, meaning increasing doses are needed for the same effect

Aldosterone antagonism enhances sodium, chloride, and water excretion, and reduces the excretion of potassium, ammonium, and phosphate

[1] Current evidence does not support pancreatic cancer as an established risk