Brain Brain-derived GLP-1 is primarily produced in specific populations of neurons expressing the GLP-1 precursor, preproglucagon (PPG) in the nucleus tractus solitarus (NTS) of the hindbrain and project to multiple brain regions that express the GLP-1R
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Modifications on the tetrahydroquinoline scaffold targeting a phenylalanine cluster on Gper as antiproliferative compounds against renal, liver and pancreatic cancer cells
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