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Curr Opin Nephrol Hypertens 29:128135 Suzuki T, Yamamoto M (2015) Molecular basis of the Keap1Nrf2 system

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doi: 10.1038/npp.2011.277 221 Martn-HernndezDTendilla-BeltrnHMadrigalJLMGarca-BuenoBLezaJCCasoJR

Patients with advanced motor symptoms, severe cognitive decline, or other significant health conditions might not be good candidates for treatment