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As we age, fat accumulation, especially visceral fat, contributes to a host of age-related issues, including inflammation and reduced energy levels
In 3T3-L1 adipocytes, NNMT inhibition raised NAD+ roughly 1.2-1.6 fold and increased cellular energy expenditure
So, can I just use supplements
Its important to check their vitamin B12 levels often to adjust their treatment
Importantly, in the same paper the anti-obesity efficacy experiment in diet-induced obese mice was carried out by systemic administration of the inhibitor the researchers did not report an oral-gavage efficacy arm
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