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If your aim is to reduce cardiovascular disease, restricting its use to a limited time only and for those with the highest BMIs doesnt make sense. The SELECT trial enrolled 17,604 adults aged 45 years and older with a BMI of 27 kg/m2 or higher and established atherosclerotic CVD

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change in mean fasting plasma glucose (FPG) at Week 30

One careful evaluation of the recipients of G6PD-deficient blood uncovered no deleterious consequences