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This binding triggers several important physiological responses: enhanced insulin secretion from pancreatic beta cells in response to elevated blood glucose, suppression of glucagon release (which normally raises blood sugar), delayed gastric emptying (slowing food passage from stomach to intestine), and increased satiety through effects on appetite centres in the brain
doi: 10.1016/j.jconrel.2004.07.010 23 Di StefanoA.SozioP.IannitelliA.MarianecciC.SantucciE.CarafaM