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No other peptide in this class shows simultaneous GI and musculoskeletal activity in animal models

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Studies demonstrate that Dihexa promotes dendritic spine formation, increases synaptic density, and enhances miniature excitatory postsynaptic currents (mEPSCs), indicating the formation of functional glutamatergic synapses

In the Phase 3 REDEFINE 1 trial, CagriSema produced a mean body weight reduction of approximately 22.7% from baseline at 68 weeks in adults with obesity (without type 2 diabetes)

For GI-specific indications, local mucosal action is sufficient and does not require systemic absorption

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