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Some people experience more gas at first, especially if they ramp up fiber too quickly

Certain medications are known to slow the digestive tract, especially pain medications or drugs that affect nerve signaling

Excess body weight increases hydrostatic pressure in the venous and lymphatic systems, elevates inflammatory cytokines, and may directly damage lymphatic vessels through lipotoxicity and chronic low-grade inflammation

Presented for research literature review only Nahata MC et al

Am J Clin Nutr 101 , 218227, (2015)

GLP-1 use is safe and effective with many pre-existing conditions with the exception of the following: Currently pregnant Currently breastfeeding Currently being treated for cancer Active eating disorder Active gallbladder disease Active substance abuse or dependency Type 1 diabetes Bariatric surgery (within the past 18 months) Pancreatitis within the past 6 months, or a history of pancreatiitis caused by taking a GLP-1 Personal or family history of medullary thyroid cancer or MEN syndrome Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)